Lenz, diffuse large B cell lymphoma

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Gene expression profiling of 420 DLBCL patient samples. The retrospective study included 181 clinical samples from CHOP-treated patients and 233 clinical samples from Rituximab-CHOP-treated patients.


Information about this file
GenomicScape ID GS-DT-20
Species Homo sapiens
Cell types Lymphoma
Study types Gene expression by array
Plateform/chip Affymetrix Human Genome U133 Plus 2.0 Array
Normalization MAS5
Log2 scale ? yes
Number of samples 420
Grouping factors abc_gcb_groups; chemotherapy; ECOG_performance_status; number_of_extranodal_sites; stage; sex
Continuous factors age
ldh_ratio
Survival data OS|OS_years|Overal survival
External database Name: GEO | ID: GSE10846 | Link: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE10846
Citations Lenz G, Wright G, Dave SS, Xiao W et al. Stromal gene signatures in large-B-cell lymphomas. N Engl J Med 2008 Nov 27;359(22):2313-23. PMID: 19038878

Cardesa-Salzmann TM, Colomo L, Gutierrez G, Chan WC et al. High microvessel density determines a poor outcome in patients with diffuse large B-cell lymphoma treated with rituximab plus chemotherapy. Haematologica 2011 Jul;96(7):996-1001. PMID: 21546504
Organization National Cancer Institute, Metabolism Branch, Bethesda, USA
Contact Name: Louis,M.,Staudt; Email: lstaudt@mail.nih.gov; Phone: 301-402-1892; Fax: 301-496-9956; Laboratory: Louis M Staudt; Department: Metabolism Branch; Institute: National Cancer Institute; Address: 9000 Rockville Pike, Bldg 10, Rm 4N114; City: Bethesda; State: MD; Zip/postal_code: 20892; Country: USA
File name code homo-sapiens_lymphoma_gene-expression-by-array_affy-hg-u133p2_mas5_GSE10846_GS-DT-20_2014-06-28
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Size 37.43 Mb
Upload date 06/28/14
Publication date 06/28/14
Date of release or last update 03/11/15
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