Herold, chronic lymphocytic leukemia, HGU133AB

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Analysis of 151 samples of peripheral blood mononuclear cells (107 HGU-133plus2; 44 HGU-133A; 44 HGU-133B) from adult patients with chronic lymphocytic leukemia (CLL).

The data provided here are the log2 gene expression profile of the 44 samples on HGU-133AB. Normalization was performed using the Robust Multichip Average (RMA) method. Only the 44754 probe sets present on A, B chips and the 2.0 chips were included in the analysis.


Information about this file
GenomicScape ID GS-DT-51
Species Homo sapiens
Cell types Leukemia
Study types Gene expression by array
Plateform/chip Affymetrix Human Genome U133 A/B
Normalization RMA
Log2 scale ? yes
Number of samples 44
Grouping factors cell_subpopulations
Survival data OS|OS_DAYS|Overall survival
External database Name: GEO | ID: GSE22762 | Link: http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE22762
Citations Herold T, Jurinovic V, Metzeler KH, Boulesteix AL et al. An eight-gene expression signature for the prediction of survival and time to treatment in chronic lymphocytic leukemia. Leukemia 2011 Oct;25(10):1639-45. PMID: 21625232

Herold T, Mulaw MA, Jurinovic V, Seiler T et al. High expression of MZB1 predicts adverse prognosis in chronic lymphocytic leukemia, follicular lymphoma and diffuse large B-cell lymphoma and is associated with a unique gene expression signature. Leuk Lymphoma 2013 Aug;54(8):1652-7. PMID: 23189934
Organization University Hospital Grosshadern, Ludwig-Maximilians-University (LMU)
Contact Name: Tobias Herold; Email: tobias.herold@med.uni-muenchen.de; Department: Department of Internal Medicine III; Institute: University Hospital Grosshadern, Ludwig-Maximilians-University (LMU); Address: Marchioninistr. 15; City: Munich; Zip/postal_code: 81377; Country: Germany
File name code homo-sapiens_leukemia_gene-expression-by-array_affy-hg-u133ab_rma_GSE22762_GS-DT-51_2015-06-30
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Size 3.24 Mb
Upload date 06/30/15
Publication date 06/30/15
Date of release or last update 06/30/15
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